Chloroform
نویسنده
چکیده
منابع مشابه
Demonstrating a natural origin of chloroform in groundwater using stable carbon isotopes.
Chloroform has been for a long time considered only as an anthropogenic contaminant. The presence of chloroform in forest soil and groundwater has been widely demonstrated. The frequent detection of chloroform in groundwater in absence of other contaminants suggests that chloroform is likely produced naturally. Compound-specific isotope analysis of chloroform was performed on soil-gas and groun...
متن کاملExtraction and determination of chloroform in rat blood and tissues by gas chromatography-electron-capture detection: distribution of chloroform in the animal body.
We have developed a simple, sensitive, and accurate method for the determination of chloroform in rat blood, brain, kidney, liver, and fat. The detection limit is 2.5 ng of chloroform per gram of tissue. Studies of in vivo distribution of chloroform in rat blood and target tissues after intragastric intubation of chloroform/water show that the amount of chloroform accumulated in the different t...
متن کاملChloroform induction of ornithine decarboxylase activity in rats.
Chloroform is a drinking water contaminant that has been demonstrated to be carcinogenic to mice and rats resulting in an increased incidence of liver and kidney tumors, respectively. The mechanism of chloroform carcinogenicity might be by tumor initiation and/or promotion. Since induction of ornithine decarboxylase (ODC) activity has been proposed as a molecular marker for tumor promoters, we ...
متن کاملOxidation of chloroform in an aerobic soil exposed to natural gas.
Acclimation of a sandy soil to an air-natural gas mixture stimulated the biological oxidation of chloroform to carbon dioxide. Acetylene and methane inhibited chloroform oxidation. Chloroform oxidation continued up to 31 days in the absence of methane. Chloroform oxidation rates increased at chloroform concentrations up to 5 mug g of soil.
متن کاملThe Pore Loop Domain of TRPV1 Is Required for Its Activation by the Volatile Anesthetics Chloroform and Isoflurane s
The environmental irritant chloroform, a naturally occurring small volatile organohalogen, briefly became the world’s most popular volatile general anesthetic (VGA) before being abandoned because of its low therapeutic index. When chloroform comes in contact with skin or is ingested, it causes a painful burning sensation. The molecular basis for the pain associated with chloroform remains unkno...
متن کاملDisinfection of swimming pools with chlorine and derivatives: formation of organochlorinated and organobrominated compounds and exposure of pool personnel and swimmers
Chlorination of pool water leads to the formation of many by-products, chloroform usually being the most abundant. The paper reports the results of a study evaluating exposure of bathers and pool employees to trihalomethanes (chloroform, bromodichloromethane, dibromochloromethane, bromoform) in four indoor swimming pools with chlorinated water. Chloroform concentrations in environmental air sam...
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